AR
ARWR
-4.2%🟢 Fundamentally supportedArrowhead Research Corporation · Healthcare
$56.06Vol 1.77M · 0.8× normalMkt cap −$0.34BMarket closed — 2026-10-16 session
What happened
Move
-4.2%
Price
$56.06
Volume
1.77M
0.8× normal
Market cap
$7.92B
−$0.34B today
Why it moved
Guidance loweredmedium confidence
- Alnylam Pharmaceuticals (ALNY) vs. IONS and ARWR: Can Pipeline Growth Restore Confidence After the Guidance Cut? — finnhub-news
- Arrowhead Pharmaceuticals, Inc. (ARWR) Discusses ARO-MAPT Interim Results and TRiM CNS Delivery Platform in Investigational CNS Pipeline Transcript — finnhub-news
Possible catalyst: guidance lowered, 3.0pp below its sector.
Verdict — was the move justified?
🟢 Fundamentally supported
Guidance lowered — direction and rough magnitude are consistent with the identified fundamental catalyst.
How unusual is this move
σ score
1.4σ
vs own 20d volatility
Percentile
76th
of 1272 daily moves
Avg daily move
±2.9%
own 5y average
vs sector
-3.0%
beyond sector median
What happened after similar moves
189 similar down moves in ARWR’s 5-year history:
After 5 days
+0.4%
52% higher
After 20 days
+0.4%
51% higher
Median of same-direction moves within ±35% magnitude band. Past patterns don’t predict outcomes — context, not signal.
Fundamental context
V 40G 25P 0H 68Q 15
Insider activity (90d): net selling $1.19M
Valuation context
P/E (TTM)
40.1
5y median 44.4
P/E percentile
15%
vs own 0y history
FCF yield
0.0%
Trading cheaper than 85% of its own historical valuation range.
Full fundamental analysis on PreMarketPrice
Pillar scores, financial statements, valuation history, news & more for ARWR