PT
PTGX
-4.0%🔴 Potential overreactionProtagonist Therapeutics, Inc · Healthcare
$139.02Vol 673.8K · 0.8× normalMkt cap −$0.38Bafter · 2026-10-13 ET
What happened
Move
-4.0%
Price
$139.02
Volume
673.8K
0.8× normal
Market cap
$9.00B
−$0.38B today
Why it moved
Analyst upgradelow confidence
- UBS Initiates Coverage On Protagonist Therapeutics with Buy Rating, Announces Price Target of $184 — finnhub-news
- Leerink Partners Assumes Protagonist Therapeutics at Outperform, Raises Price Target to $190 — finnhub-news
Weak signal: analyst upgrade, 3.2pp below its sector.
Verdict — was the move justified?
🔴 Potential overreaction
A 2.6σ move well beyond the sector with no identified fundamental or news driver — the reaction appears larger than currently visible evidence justifies. Likely flow/positioning-driven.
How unusual is this move
σ score
2.6σ
vs own 20d volatility
Percentile
82th
of 1265 daily moves
Avg daily move
±2.7%
own 5y average
vs sector
-3.2%
beyond sector median
What happened after similar moves
171 similar down moves in PTGX’s 5-year history:
After 5 days
+1.7%
61% higher
After 20 days
+6.2%
68% higher
Median of same-direction moves within ±35% magnitude band. Past patterns don’t predict outcomes — context, not signal.
Fundamental context
V 10G 0P 82H 75Q 35
Insider activity (90d): net selling $18.65M
Valuation context
P/E (TTM)
113.1
5y median 52.5
P/E percentile
79%
vs own 2y history
FCF yield
0.0%
Trading richer than 79% of its own historical valuation range.
Full fundamental analysis on PreMarketPrice
Pillar scores, financial statements, valuation history, news & more for PTGX